Mitomycin induction
Web7 mei 2010 · Bacteriophages infecting Staphylococcus epidermidis were isolated by mitomycin C induction. Three distinct phages (vB_SepiS-phiIPLA5, vB_SepiS … Webincrease induction rates via hydrogen-peroxide pro- duction from photodegradation of organic matter (Petasne & Zika 1987, Johnson et al. 1989). Our study estimated the percentage of lysogens that could be induced by mitomycin C, solar radiation and hydrogen peroxide along a transect from oceanic to neritic
Mitomycin induction
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Web25 dec. 1982 · In exponentially growing cultures of E. coli AB 1157, the addition of mitomycin C (5 micrograms/ml) promotes a 15-fold increase of the content of recA protein with respect to the basal level. Kinetic analysis of this induction shows that the maximum is reached 60 to 90 min after the addition of the drug and then the level decreases. WebInduction of phage formation in the lysogenic Escherichia coli K-12 by mitomycin C. Induction of phage formation in the lysogenic Escherichia coli K-12 by mitomycin C. …
Web6 dec. 2024 · Mitomycin C acts on DNA in three possible ways: promoting (a) cross-linking events, (b) alkylation and not necessarily cross-linking, and (c) strand breakage. … WebMitomycin selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of mitomycin-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed. In humans, mitomycin is rapidly cleared from the serum after intravenous ...
Web26 okt. 2024 · Next, mitomycin gel demonstrated a favourable tolerability and safety profile, given that only three patients (10%) discontinued induction therapy, and no Grade 4–5 adverse events occurred. One notable complication of the antegrade approach occurred in a patient with a PCNT, which was likely placed through a peripelvic cyst and subsequently … Web19 nov. 2014 · A prophage vB_CibM-P1 was induced by mitomycin C from the epipelagic strain Citromicrobium bathyomarinum JL354, a member of the alpha-IV subcluster of marine aerobic anoxygenic phototrophic ...
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WebThese generally occur when mitomycin is used in combination with other chemotherapeutic agents, particularly vinca alkaloids (Castro et al. 1996; Rivera et al. 1995). The mechanism of mitomycin-induced pulmonary toxicity is unknown, but may be related to inhibition of cell proliferation and repair of pulmonary endothelium (Hoorn et al. 1995). chemistry scopus indexed journalsWebMitomycin is one of the older chemotherapy drugs, which has been around and in use for decades. It is an antibiotic which has been shown to have antitumor activity. Mitomycin selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of mitomycin-induced cross-linking. flight hpn to atlantaWebMitomycin for Injection is a sterile dry mixture of mitomycin and mannitol, which, when reconstituted with Sterile Water for Injection, provides a solution for intravenous … flight hpn to gnvWeb21 dec. 2024 · Characterization of effect of mitomycin C and UV exposure. Our results showed that bacterial grow is not disrupted by mitomycin C induction at early stages of induction (15 and 45 min) ().Contrastingly, both mitomycin C and UV triggered growth difference in both uninduced cultures and induced cultures in late induction stages (). ... flight hpn to atlWeb29 mrt. 2024 · Upon induction by mitomycin C, the PtoH ratio increased to 14.56 (+/−1.18 sd). The difference of PtoH ratios between induced and control cultures (ΔPtoH ratio), calculated as the mean log 2 -fold change (l 2 fc) of PtoH ratios (Fig. 1 c; see also the ‘ Methods ’ section: formula iii), was 3.65 (+/−0.13 sd). Fig. 1 chemistry scotlandWeb1 apr. 1997 · MMC-induced HUS is characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and renal thrombotic microangiopathy; other … flight hrl to nboWeb24 aug. 2024 · For mitomycin C induction tests, 50 ml RCM was inoculated from saturated culture at an OD 600nm ~ 0.05, inverted several times for gentle mixing, and grown at 37 °C in anaerobic chamber for 4–5 ... flight hpn to fll