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WebOccupational Safety and Health Administration. UNITED STATES DEPARTMENT OF LABOR. Facebook; Twitter; Instagram; RSS; Subscribe; YouTube WebBoth VDRL and RPR quantitative titer usually correlate with disease activity, and are used to monitor the effect of treatment. If treatment is successful, the antibody titer gradually declines. A four-fold change in titer (e.g., from 1:16 to 1:4) is necessary to demonstrate a clinically significant difference between two nontreponemal tests. boxer throws punches at thin air
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